Notizie AIOM – anno XVII
FDA Approves NovoTTF-100L Plus Chemo for Malignant Pleural Mesothelioma
May 23, 2019 - The FDA has approved the NovoTTF-100L System in combination with pemetrexed and platinum-based chemotherapy for the frontline treatment of patients with unresectable, locally advanced or metastatic malignant pleural mesothelioma (MPM), marking the first treatment ...Leggi tutto
FDA Grants LN-145 Breakthrough Designation for Cervical Cancer
May 24, 2019 - The FDA has granted a breakthrough therapy designation to the tumor-infiltrating lymphocyte (TIL) therapy LN-145 for the treatment of patients with recurrent, metastatic, or persistent cervical cancer with disease progression on or after chemotherapy, according ...Leggi tutto
FDA Approves Ruxolitinib for Steroid-Refractory Acute GVHD
May 24, 2019 - The FDA has approved ruxolitinib for the treatment of adult and pediatric patients ≥12 years of age with steroid-refractory acute graft-versus-host disease (aGVHD). THe approval is based on findings from the phase II REACH1 trial, which demonstrated ...Leggi tutto
FDA Approves Alpelisib for Breast Cancer
May 24, 2019 - The FDA has approved the PI3K inhibitor alpelisib for use in combination with fulvestrant as a treatment for postmenopausal women, and men, with HR-positive, HER2-negative, PIK3CA-mutated, advanced or metastatic breast cancer following progression on or after ...Leggi tutto
EMA facilitates early engagement with medicine developers to combat antimicrobial resistance
May 24, 2019 - As of today, EMA is opening up the early dialogue available through its Innovation Task Force (ITF) to all medicine developers who work on therapeutic approaches for the treatment or prevention of bacterial and fungal infections. ITF is a forum for dialogue ...Leggi tutto
ASCO Supports the Tobacco-Free Youth Act
May 21, 2019 - “ASCO strongly supports this strong, bipartisan bill that would raise the federal age for purchasing tobacco products, electronic cigarettes, and alternative nicotine products from 18 to 21 nationwide. This legislation represents an important federal ...Leggi tutto
Update of EU recommendations for 2019–2020 seasonal flu vaccine composition
May 20, 2019 - EMA has issued an update of the EU recommendations for the influenza virus strains that vaccine manufacturers should include in vaccines for the prevention of seasonal influenza from autumn 2019. The recommendations now also contain a decision on suitable ...Leggi tutto
Local Consolidative Therapy Vs. Maintenance Therapy or Observation for Patients With Oligometastatic Non-Small-Cell Lung Cancer: Long-Term Results of a Multi-Institutional, Phase II, Randomized Study
Our previously published findings reported that local consolidative therapy (LCT) with radiotherapy or surgery improved progression-free survival (PFS) and delayed new disease in patients with oligometastatic non–small-cell lung cancer (NSCLC) that did not progress ...Leggi tutto
Lifetime Occurrence of Brain Metastases Arising from Lung, Breast, and Skin Cancers in the Elderly: A SEER-Medicare Study
The Surveillance, Epidemiology, and End Results (SEER) Program recently released data on brain metastases (BM) diagnosed during primary cancer staging workup (“synchronous” BM, or SBM); this study examines the incidence of SBM compared with that of lifetime BM ...Leggi tutto