Notizie AIOM – anno XIV n. 566
Racial and Ethnic Variations in Lung Cancer Incidence and Mortality: Results From the Women’s Health Initiative
This study aimed to evaluate racial/ethnic differences in lung cancer incidence and mortality in the Women's Health Initiative Study, a longitudinal prospective cohort evaluation of postmenopausal women recruited from 40 clinical centers. Lung cancer diagnoses were centrally ...Leggi tutto
Missing Patients’ Symptoms in Cancer Care Delivery – The Importance of Patient-Reported Outcomes
As cancer care professionals, we care deeply about our patients’ symptoms. Indeed, symptom management is a cornerstone of oncology practice. Yet, many studies demonstrate that we consistently miss up to half of our patients’ symptoms. Several years ago, a methodologist ...Leggi tutto
Self-Evaluation of Adjuvant Chemotherapy-Related Adverse Effects by Patients With Breast Cancer
Patient perspective on chemotherapy-related adverse effects is being increasingly acknowledged both in experimental clinical trials and in clinical practice. To evaluate a 10-item, paper questionnaire derived from the US National Cancer Institute’s Common Terminology ...Leggi tutto
Temsirolimus Maintenance Therapy After Docetaxel Induction in Castration-Resistant Prostate Cancer
Temsirolimus maintenance therapy after docetaxel induction chemotherapyis safe in patients with castration-resistant prostate cancer, although biochemical or tumor responses are rare;does not diminish quality of life; anddelays radiological and/or symptomatic progression ...Leggi tutto
The Genetic Evolution of Melanoma from Precursor Lesions
The pathogenic mutations in melanoma have been largely catalogued; however, the order of their occurrence is not known. We sequenced 293 cancer-relevant genes in 150 areas of 37 primary melanomas and their adjacent precursor lesions. The histopathological spectrum of these ...Leggi tutto
Randomized Double-Blind Trial of Pregabalin Versus Placebo in Conjunction With Palliative Radiotherapy for Cancer-Induced Bone Pain
Cancer-induced bone pain (CIBP) affects one third of patients with cancer. Radiotherapy remains the gold-standard treatment; however, laboratory and clinical work suggest that pregabalin may be useful in treating CIBP. The aim of this study was to examine pregabalin in patients ...Leggi tutto